Fabrication of 3D Microstructured and Collagen Scaffolds with Chondrogenic Cells and Translational Application for Cartilage Regeneration (REGEN)


Project no.: SEN-15092

Project description:

Osteoarthritis is a degenerative joint injury, especially of older people, which is caused of cartilage damage. There is still no effective cartilage structure restoring treatment, though recently attention is paid to biological cartilage regeneration, using autologous chondrocyte implantation. In order to increase the effectiveness of treatment, it is necessary to improve procedures for cell isolation, cultivation, and growing on the scaffold. The project aims to develop and characterize the most effective 3D scaffold with animal (rabbit) and human cells. Results will be applied in search for an optimal type of scaffold and production methods.

Project funding:

Research Council of Lithuania (RCL), National Research Programme “Healthy Ageing”

Project results:

The development of 3D scaffolds for rabbit chondrocytes and human chondrogenic cells cultivation and growing and the evaluation in vitro of human stem cells possibilities to form a cartilage tissue using these scaffolds.

Period of project implementation: 2015-10-01 - 2018-05-31

Project coordinator: Lithuanian University of Health Sciences

Project partners: Vilnius University, Kaunas University of Technology

Virginija Jankauskaitė

2015 - 2018

Department of Production Engineering, Faculty of Mechanical Engineering and Design

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