An outbreak of the coronavirus SARS-CoV-2 led to the pandemic of COVID-19 disease, threatening human lives worldwide. Quarantine, the most effective pandemic restrain measure, is appropriate only in short term. The efficient control of virus spreading, achieved without sacrificing economic and social well-being, appears paramount for COVID-19 restrain. Spread of SARS-CoV-2 is directly linked to virus ability to maintain the infectivity, property forbidden for direct testing. Therefore, the proper evaluation system of SARS-CoV-2 inactivating treatment is of special value for discovery and development of specific antiviral compounds. Ideal system would be virus based on the same genetic material, simple structure, efficient replication in the host cell. Thus the idea of the Proposal is knowledge-based use of safe yeast Saccharomyces cerevisiae viral system in selection of the COVID-19 pathogen-inactivating compounds. The goal is elaboration of original, safe and easy to use model system and following its application for development of broad spectra disinfection and skin protection products along with new pharmacological forms. The tasks of Proposal include formulation of new, safe to use products and defined methodic and practical recommendations, enabling the control of COVID-19 pathogen spread in pharmacies and general management of extreme situations.
Research Council of Lithuania, short-term research (in health, social and other fields), analysis and implementation of diagnostics, related to COVID-19. Project is funded from financial sources under the 2021-2027 Operational Programme for the European Union Funds’ Investments.
Period of project implementation: 2021-04-15 - 2021-12-31
Project coordinator: Vilnius University
Project partners: Nature Research Centre, Kaunas University of Technology