Derivatives of pyrazole, chromene, and quinoline are commonly found in drug structures. The task of the project is to develop new pyrazole derivatives containing quinoline and chromene fragments and to analyze their structure and properties. The project will involve the synthesis of pyrazole derivatives from readily available starting compounds; synthesis and functionalization of polycyclic pyrazole, chromene and quinoline ring systems using modern organic synthesis methods; detailed structural studies of newly obtained polyheterocyclic systems using modern spectroscopy, spectrometry, X-ray structural analysis and other methods; studies of optical and biological activity properties. The results of the project will be announced in the student’s oral presentation.
Project funding:
Project is funded by EU Structural Funds according to the 2014–2020 Operational Programme for the European Union Funds’ Investments priority “Development of scientific competence of researchers, other researchers, students through practical scientific activities” under Measure No. 09.3.3-LMT-K-712.
Project results:
As a result of the project synthesis of new pyrazole derivatives with chromene and quinoline fragments was performed, their structure was determined, their biological properties were investigated, and the student’s skills in the field of organic chemistry were strengthened.
Period of project implementation: 2021-09-01 - 2022-03-31
Project coordinator: Kaunas University of Technology
