Micro- and nanohydrogels based on structured natural polysaccharides in the last decade are actively studied as polymeric materials for medical purposes. In particular, this includes an investigation of stimulus-sensitive hydrogels for encapsulation of biologically active compounds, the design of hydrogel semipermeable membranes for dialysis, and the investigation of polysaccharide cross-linked microhydrogels for therapeutic drug delivery systems. The use of natural polysaccharides for these purposes is due to their tolerance to the human body, i.e. when introduced into the human body, natural polysaccharides do not cause toxic effects both at the cytological and general level. In general, polysaccharides are biodegradable, and their destruction products are also non-toxic and easily eliminated from the body. The aim of the project is synthesis and investigation of new functionalized polymeric materials based on polysaccharides with dendrimeric and / or cross-linked structures. The multifunctionality of the obtained polymers will be achieved through the introduction of (1) fragments providing a response to environmental factors and (2) chromophore groups able to locate microgel particles in various media and investigate their properties.
Project funding:
Intergovernmental programme administrated by Research Council of Lithuania: Lithuania–Ukraine
Project results:
The structured agents with various functional properties will be synthesized and used in the synthesis of structured polysaccharides. Structured polysaccharides responding to environmental factors will be synthesized and their properties will be investigated.
Period of project implementation: 2022-01-18 - 2023-12-31
Project coordinator: Kaunas University of Technology
Project partners: Lviv Polytechnic National University
