Formation, investigation and application of structured nano-composites for nano/micro bioparticles analysis and manipulation (BioSensor)

 

Project no.: P-MIP-19-39

Project description:

This project is intended for the facilities and technologies conditioning the further development of modern single molecule based biosensors. It is planned to develop micromechanical fluidic devices and bio particle control technologies based on the principle of bulk acoustic wave generation in piezoelectric nanocomposite and functional capabilities of nano/micro cavities formed in it to trap, position and transport the bio-particles. Such technologies have potential not only to be applied for the development of biosensors, but as well in cytometry for applications in diagnostics of different kind damages (injuries) at the cell level. This will be achieved by synthesizing lead free piezoelectric nano composite, evaluating its mechanical, electrical, hydrophobic and dynamic properties, and developing technologies for nano/micro cavities and microstructure formation in piezoelectric nano composite. For achieving the set tasks, theoretical and experimental research will be carried. Theoretical research includes the application of bulk acoustic wave for bio particles control and analysis of the influence of the properties of piezoelectric nanocomposite materials on the functionality of micro fluidic system. Evaluation of mechanical, electrical, hydrophobic and dynamic properties of piezoelectric nanocomposite, and analysis of the potential of their application in developing trapping and positioning components of bio particles together ensuring their transportation possibilities will be done. In addition, it is planned to design functional prototype of acoustophoresis micromechanical fluidic element, functioning on the principle of bulk acoustic wave generation. Results obtained in this project will be significant for the development of a new generation biosensors.

Project funding:

Projects funded by the Research Council of Lithuania (RCL), Projects carried out by researchers’ teams

Period of project implementation: 2019-05-31 - 2022-06-30

Project coordinator: Kaunas University of Technology

Head:
Giedrius Janušas

Duration:
2019 - 2022

Department:
Department of Mechanical Engineering, Faculty of Mechanical Engineering and Design