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A Next-Generation Biomedical Platform Enabling Molecular Radiation-Harvesting Centers for Dosimetry Applications

 

Project no.: S-MIP-25-20

Project description:

The BioRHAD project proposes the development of a next?generation molecular dosimetry platform tailored for biomedical applications. It aims to address critical limitations in current radiation detection technologies by designing novel organic molecules that incorporate boron and gadolinium?based radiation?harvesting centers. These compounds will be integrated into sensor devices capable of real?time, multimodal detection of ionizing radiation (neutrons, protons, X?rays) with high sensitivity and spatial resolution.
The interdisciplinary project unites expertise from Vilnius University and Kaunas University of Technology, combining advanced organic synthesis, device engineering, and biomedical testing. The platform will be validated through exposure to various radiation sources and tested in simulated biological environments, including cancer cell models. The project’s iterative development model ensures rapid optimization and adaptation of materials and devices.

Project funding:

Research Council of Lithuania, Projects carried out by researchers’ teams


Project results:

Expected outcomes include novel molecular structures, functional sensor prototypes, and comprehensive datasets on radiation interaction. The project will contribute to improved diagnostic precision in radiotherapy, foster international collaboration, and support the training of
early?career researchers. Dissemination will occur through open?access publications, conferences, and public engagement activities, with potential for intellectual property and future clinical translation.

Period of project implementation: 2025-11-03 - 2028-10-31

Project coordinator: Vilnius University

Project partners: Kaunas University of Technology

Head:
Simona Urnikaitė

Duration:
2025 - 2028

Department:
Department of Organic Chemistry, Faculty of Chemical Technology