“Rare Forest and Coastal-dune Mushroom: Evaluation of Antioxidant and Biological Properties” Doctoral Thesis

Author, Institution: Lina Smolskaitė, Kaunas University of Technology

Science area, Field of science: Physical  Sciences,Chemistry – 03P

Scientific Supervisors:

Prof. Dr. Petras Rimantas VENSKUTONIS (Kaunas University of Technology, Physical Sciences, Chemistry – 03P).
Dr. Thierry TALOU (University of Toulouse, Physical Sciences, Chemistry – 03P).

The Doctoral Dissertation is available  at the libraries of Kaunas University of Technology (K. Donelaičio St. 20, Kaunas)

Dissertation defence board of Chemistry science field:

Prof. Dr. Habil. Algirdas Šačkus (Kaunas University of Technology, Physical Sciences, Chemistry – 03P) – chairman,
Prof. Dr. Nicolas FABRE (Paul Sabatier – Toulouse III University, France, Prancūzija, Physical Sciences, Chemistry – 03P),
Dr. Herve HOSTE (French National Institute for Agricultural Research, France,  Biomedical Sciences, Zoology – 05B),
Prof. Dr. Daiva LESKAUSKAITĖ (Kaunas University of Technology, Technological Sciences, Chemical Engineering – 05T),
Assoc. Prof. Dr. Audrius PUKALSKAS (Kaunas University of Technology, Physical Sciences, Chemistry – 03P).

Annotation:

Due to the metabolic diversity, ecological variety, significant role in nature and complicated web of life cycles, fungi have attracted the attention of various scientists, mycologists, chemists, biologists and pharmacists in multiple ways. A large, untapped, and chemically diversity resource of bioactive metabolites from wild macrofungi provide increasing opportunities for finding new lead structures for medicinal, nutritional, functional, therapeutic and phytochemical chemistry. The main aim of this study was to investigate antioxidant, antimicrobial and other bioactivities of the selected underinvestigated wild mushroom species to obtain scientific information, which is required for their valorisation as a source for human nutrition and production of functional ingredients. In this study, comprehensive and systematic evaluation of antioxidant and antimicrobial properties of wild mushroom species provides important data for their further valorisation as a source of valuable ingredients. More specifically, the extracts isolated from the species possessing the strongest antioxidant potential may be promising protecting agents against oxidative damage and inhibitors of gastrointestinal nematodes. The principal components of such species, hispidin, hispolon and inonotic acid methyl ester may represent a group of new natural compounds for developing functional ingredients for nutraceuticals, functional foods, pharmaceuticals and other applications.