Author, institution: Sandra Kiseliovienė, Kaunas University of Technology
Science area, field: Physical sciences, Chemistry – 03P
The Doctoral Dissertation is available at the library of Kaunas University of Technology (K. Donelaičio St. 20, Kaunas).
Scientific Supervisor: Prof., Dr. Jolanta LIESIENĖ (Kaunas University of Technology, physical sciences, chemistry – 03P).
Dissertation defence board of Chemistry Science Field:
Prof. Dr. Habil. Algirdas Šačkus (Kaunas University of Technology, Physical sciences, Chemistry – 03P), chairman,
Prof. Dr. Saulius Grigalevičius(Kaunas University of Technology, Physical sciences, Chemistry – 03P),
Assoc. Prof. Dr. Jolita Ostrauskaitė (Kaunas University of Technology, Physical sciences, Chemistry – 03P),
Dr. Aiva Plotniece (Latvian Institute of Organic Synthesis, Latvija, Physical sciences, Chemistry – 03P),
Prof. Dr. Skaidra Valiukevičienė (Lietuvos University of Health Sciences, Biomedical sciences, medicine – 06B).
Annotation:
Recently, in chemistry and material sciences, a new generation of wound dressings has been extensively developed. Dressings made of new forms such as sponges, films and hydrocolloids have been developed together with new functions. Modern bandages not only protect the wound from infection, but as well promote the healing process, irrigate the wound, absorb the wound secretions, achieve the desired pH of the wound medium, stimulate the necessary growth factors and carry active compounds into the wound. Wound dressing should create an optimal environment that allows unrestricted movement of epithelial cells. The optimal conditions for wound healing are a moist environment around the wound and an effective oxygen circulation, which promotes cell and tissue regeneration. Natural polymers (collagen, alginates, chitosan, cellulose derivatives, etc.) are widely used for the non-healing wounds. Cellulose as a natural, non-irritant, nontoxic, biocompatible, environmentally friendly material is widely used as a wound healing material. As a wound dressing, cellulose is used in various forms. As a hydrogel form is becoming more and more popular, cellulose hydrogels are becoming a field of interest as well.
For the first time, the regenerated cellulose hydrogel was used for the preparation of wound dressing material. It has been shown that the structure and the properties of regenerated cellulose could be easily modified by the lyophilisation or treating with supercritical CO2.
