Author, Institution: Dovilė Liudvinavičiūtė, Kaunas University of Technology
Science area, field of science: Technological Sciences, Chemical Engineering, T005
Scientific Supervisors:
2019–2020 Assoc. Prof. Dr. Ramunė Rutkaitė ( Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005)
2016–2019 Assoc. Prof. Dr. Rima Klimavičiūtė (Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005)
Scientific Advisor:
2018–2019 Assoc. Prof. Dr. Ramunė Rutkaitė (Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005)
Dissertation Defence Board of Chemical Engineering Science Field:
Prof. Dr. Habil. Juozas Vidas Gražulevičius (Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005) – chairman
Prof. Dr. Jurga Bernatonienė (Lithuanian University of Health Sciences, Medicine and Health Sciences, Pharmacy, M003)
Prof. Dr. Jolita Ostrauskaitė (Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005)
Prof. Dr. Petras Rimantas Venskutonis (Kaunas University of Technology, Technological Sciences, Chemical Engineering, T005)
Dr. Evelyn Wolfram (Zurich University of Applied Sciences, Switzerland, Technological Sciences, Chemical Engineering, T005)
The dissertation defence takes place online.
The doctoral dissertation is available at the library of Kaunas University of Technology (K. Donelaičio g. 20, Kaunas).
Annotation:
Anthocyanins, caffeic and rosmarinic acids are bioactive compounds that exhibit antioxidant and antimicrobial properties. These compounds are unstable as they are sensitive to changes in temperature, pH of the medium, oxidation. Immobilization of phenolic compounds in natural polysaccharides could help preserve their bioactive properties. This research is dedicated to the investigations of the interaction between caffeic, rosmarinic acids, anthocyanins and marine polysaccharides in water when forming complexes, and the evaluation of the properties of these complexes. Ionic complexes were formed in water due to the electrostatic interaction between ionized groups of marine polysaccharides and anionic or cationic groups of phenolic acids or anthocyanins, respectively. Complex formation and the amount of phenolic compounds immobilized in marine polysaccharides depend on the composition of polysaccharides, the type of the phenolic compound and the ratio of the complex-forming reagents. Prolonged antioxidant activity is characteristic of complexes of phenolic compounds and marine polysaccharides, and phenolic acids or anthocyanins can be effectively released into various media. Chitosan films containing rosmarinic acid and chitosan complexes highly soluble in a simulated gastric medium and exhibiting prolonged antioxidant activity were developed.
